Blake Krass, a veteran analyst at DraftKings, has released his latest Pick6 predictions for Wednesday’s MLB slate, spotlighting a trio of standout performers who could tip the scales in fantasy lineups.
At the top of the list is Bryce Harper, who has been on fire, batting .458 with a 1.375 OPS over the past week and maintaining a 1.036 OPS against right‑handed pitching this season. He enters the game with a career .360 average and a 1.065 OPS in 25 at‑bats versus Miles Mikolas, who sits at a 5.47 ERA and 1.28 WHIP in 2026.
Harper vs Mikolas: A Matchup to Exploit
Harper’s recent surge makes him a prime candidate to dominate Mikolas, whose recent ERA of 5.47 and WHIP of 1.28 suggest vulnerability. The historical .360 average against Mikolas underscores the upside of stacking Harper in DraftKings’ Pick6 format.
Another hot hitter, Jac Caglianone, has launched six home runs in his last five games, posting a 1.431 OPS over the past week and a 1.227 OPS in June. He will face Griffin Jax, who carries a 3.67 ERA and 1.31 WHIP this season, but left‑handed batters have posted a .282 average and .830 OPS against Jax, hinting at a favorable matchup.
Caglianone’s Power Surge Against Jax
Caglianone’s recent power output aligns perfectly with Jax’s tendencies, as left‑handed hitters have thrived against him. Expect Caglianone to add another multi‑home run night, making him a high‑upside pick in the Pick6 pool.
On the pitching side, Joe Ryan continues to impress with a 1.00 WHIP and a 2.99 ERA this season, averaging 10.2 strikeouts per nine innings and already reaching 99 strikeouts for the year. His 2.85 ERA in Minnesota in 2026 and six of his last seven starts with at least seven strikeouts further cement his reliability against the Dodgers.
Ryan’s Strikeout Potential
Ryan’s recent form suggests he could easily eclipse six strikeouts against a Dodgers lineup that has struggled with high‑velocity arms. His consistency in the Twin Cities, combined with a strong recent track record, makes him a solid anchor for any DraftKings Pick6 entry.
DraftKings’ Pick6 game lets fans construct six‑player lineups that score based on real‑world performance, offering a streamlined way to capitalize on these projected successes. To play, users select a slate of games, pick six players they expect to excel, and earn points as those players hit, run, or strike out in the actual games. The format rewards strategic stacking of high‑upside talent like Harper, Caglianone, and Ryan, turning statistical insights into tangible fantasy rewards.